Nuclear Pharmacy — Questions needed in the following areas

Procurement: High Priority

Example areas:

• USP standards for ingredients, precursors, reagents, tests and assays, vendor certificates of purity or physical/chemical means of identification
• Analytical supplies and other materials needed for quality control (e.g. solvents, columns, sterility test media, endotoxin test media)
• Storage conditions and effect on the physical and/or chemical integrity of the material
• Supplies needed to practice nuclear pharmacy (e.g. disinfectants, gloves)

Compounding: Medium Priority

Example areas:

• Shielding requirements
• Federal regulations and standards regarding inspections of drug storage areas (e.g. The Joint Commission and USP)
• Record keeping requirements to ensure traceability and recall procedures
• Impurities and their effects on patient study or stability of radiopharmaceutical (e.g. radiochemical, chemical and radionuclide)

Quality Assurance: Medium Priority

Dispensing: High Priority

Example areas:

• Dosage levels based on patient history, age, weight, pregnancy
• Adverse reaction and/or product problem investigation and reporting systems
• Sequencing when multiple imaging modalities are required
• Dosage form characteristics

Health and Safety: High Priority

• Biohazardous and ionizing radiation risks
• Receipt, storage, handling, disposal and transportation of RAM
• Knowledge of USP and sterility
• Biohazardous and/or radiation disposal policies and methods
• OSHA and CDC standards

Drugs

• Samarium-153 EDTMP
• Blood labeling techniques
• In-111 pentetreotide
• Dobutamine
• I-123 DatScan